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Jild 11 Nomeri 1 (2025)
Central Asian Research Journal for Interdisciplinary Studies (CARJIS) special issue – medicine sciences

Articles

BOLALARDA QALQONSIMON BEZ FUNKSIONAL FAOLIYATINING O‘ZGARISHLARIGA XOS NUR- ANATOMIK JIHATLARI

DOI 10.63294/afucon/vol11iss1/253 Google Scholar Google Scholar Betlar 328-334

Nashr qilingan 2025-11-30

Mualliflar
Shodiyeva Munojaat Narziqul qizi
Affiliation
Alfraganus Universiteti image/svg+xml
PDF

Annotatsiya

Ushbu ilmiy tadqiqot bolalarda qalqonsimon bez (QSB) funksional faolligining o‘zgarishlariga xos nur-anatomik xususiyatlarni o‘rganishga bag‘ishlangan. Tadqiqotda 5 yoshdan 16 yoshgacha bo‘lgan 120 nafar bola ishtirok etdi. Ular orasida 60 nafari klinik jihatdan sog‘lom bolalar (nazorat guruhi), 60 nafari esa qalqonsimon bez faoliyatida turli darajadagi o‘zgarishlarga ega bo‘lgan (eksperimental guruh) bolalar edi. Tadqiqotda ultratovush tekshiruvi, laborator gormonal tahlillar (TSH, T₃, T₄) hamda klinik ko‘rsatkichlar asosida qalqonsimon bezning strukturaviy va funksional o‘zgarishlari tahlil qilindi. Shuningdek, nur diagnostik usullarining (ultratovush, Dopplerografiya) aniqligi va ularning natijalarini immuno-gormonal ko‘rsatkichlar bilan taqqoslash orqali bez faoliyati darajasi aniqlangan. Olingan natijalar shuni ko‘rsatdiki, qalqonsimon bez faoliyatining o‘zgarishlari bolalar yoshiga, jinsiga va umumiy gormonal foniga bevosita bog‘liqdir. 5–10 yoshli bolalarda qalqonsimon bez hajmining o‘zgarishi asosan funksional moslashuv xarakterida bo‘lsa, 11–16 yosh oralig‘ida esa gormonal nomutanosiblik bilan bog‘liq morfologik o‘zgarishlar ustunlik qilgan. Tadqiqot natijalari bolalarda endokrin tizimdagi o‘zgarishlarni erta bosqichda aniqlash, nur diagnostikasi orqali ularning dinamikasini baholash hamda individual davolash strategiyasini tanlashda muhim ahamiyat kasb etadi.

References

  1. Abdullayev A.M., Tursunov N.X. Bolalarda qalqonsimon bez morfologiyasi va yoshga bog‘liq o‘zgarishlar. – O‘zbekiston Tibbiyot Jurnali, 2021; №4: 25–31
  2. Rasulova M.Z., Ahmedov S.R. Gipotiroid va gipertiroid holatlarda qalqonsimon bez ultratovush ko‘rsatkichlari. – Endokrinologiya yangiliklari, 2020; №2(15): 41–48
  3. Mamatqulova G.O., Qodirov A.S. Bolalarda qalqonsimon bez giperplaziyasi va uning gormonal profili. – Pediatriya va Radiologiya, 2019; №3(27): 56–63
  4. Safarov B.I., Karimova L.T. Yoshga xos endokrin tizim o‘zgarishlarining tibbiy ahamiyati. – Tibbiyot va biologiya axborotnomasi, 2022; №1: 14–19
  5. Ince M.N., Elliott D.E. Immunologic and molecular mechanisms in thyroid dysfunction. – The Surgical Clinics of North America, 2017; 87(3): 681–696
  6. Müzes G., Molnár B., Tulassay Z., Sipos F. Changes of the cytokine profile in thyroid- related disorders. – World Journal of Gastroenterology, 2022; 18(41): 5848–5861
  7. Chen M.L., Sundrud M.S. Cytokine networks and endocrine interactions in children. – Inflammatory Endocrine Diseases, 2016; 22(5): 1157–1167
  8. Kadirova N.N., Tajiyev B.M. Bolalarda qalqonsimon bez kasalliklarini erta aniqlashda ultratovush diagnostikasining roli. – Toshkent Pediatriya Tibbiyot Instituti Ilmiy Axborotnomasi, 2021; №2(8): 77–84
  9. Zharkova T.S., Kuznetsov S.V., Gubar S.O. The role of inflammatory mediators in thyroid function in children. – Healthcare in Tajikistan, 2017; 1(332): 15–20
  10. Ivanov I.V., Sidorova O.S., Filippova G.M. Pediatric thyroid disorders: clinical and radiological correlations. – Bulletin of Medical Sciences, 2017; 2(6): 34–37
  11. Simbirtsev A.S., Totolyan A.A. Cytokines in laboratory diagnostics of endocrine disorders. – Infectious Diseases: News, Opinions, Education, 2015; 2: 82–98

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